Este resumo de evidências não é aconselhamento médico. É um rascunho de busca bibliográfica com fontes para pesquisa e escrita acadêmica. Sempre verifique os artigos originais antes de citar ou aplicar qualquer achado.
Pergunta de pesquisa
O jejum intermitente melhora a resistência à insulina?
Resposta curta
A literatura retornada deve ser revisada quanto ao protocolo de jejum, dieta comparadora, marcador de resistência à insulina e estado metabólico.
Condições de busca e resultados
- Afirmação pesquisada: O jejum intermitente pode melhorar a resistência à insulina.
- Intenção da busca: Encontrar artigos biomédicos com fontes sobre jejum intermitente e resistência à insulina.
- Conjunto de resultados: Principais artigos biomédicos com fontes retornados pelo LitSource para esta afirmação.
- Última atualização: 2026-05-04
Principais artigos encontrados
| Artigo | Ano | Periódico | Fonte | Trecho de evidência |
|---|---|---|---|---|
| Adipocyte-derived PGE2 is required for intermittent fasting-induced Treg proliferation and improvement of insulin sensitivity. | 2022 | JCI insight | PMID 35260536 | Intermittent fasting (IF), an eating pattern that involves periods of normal eating followed by restriction (fasting), has gained attention as an effective approach to improve obesity-induced metabolic dysfunctions such… |
| Intermittent fasting: is there a role in the treatment of diabetes? A review of the literature and guide for primary care physicians. | 2021 | Clinical diabetes and endocrinology | PMID 33531076 | Interestingly, several studies have demonstrated that intermittent fasting, even in the absence of fat loss, has resulted in a reduction of leptin levels and an increase of adiponectin, which results in improvements of… |
| Dietary Strategies for Metabolic Syndrome: A Comprehensive Review. | 2020 | Nutrients | PMID 33003472 | The main cardiometabolic effects observed after an intermittent-fasting intervention are weight loss and improvements in insulin resistance, dyslipidemia, BP levels and inflammation. |
| Fasting practices in Tamil Nadu and their importance for patients with diabetes. | 2016 | Indian journal of endocrinology and metabolism | PMID 27867892 | Caloric restriction (CR) and intermittent fasting (IF) have shown to improve glucose homeostasis and insulin resistance in humans. |
| Is Fasting Good When One Is at Risk of Liver Cancer? | 2022 | Cancers | PMID 36291868 | Clinical studies have shown, apart from a significant decrease in body weight, that intermittent fasting has additional cardiometabolic benefits comprising in improvements in blood pressure, LDL cholesterol, insulin res… |
| Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects. | 2020 | Journal of proteomics | PMID 31927066 | Upregulation of PLIN4 expression one week after 30-day intermittent fasting suggests that 30-day intermittent fasting from dawn to sunset mimics PPAR-gamma activators (e.g., pioglitazone), and this may be one of the mec… |
| Intermittent fasting for weight loss in night shift workers: a three-arm, superiority randomised clinical trial. | 2025 | EBioMedicine | PMID 40554393 | We tested the effectiveness of two modified intermittent fasting (IF) strategies compared with continuous energy restriction (CER) on weight loss and improvements in insulin resistance in night shift workers. |
| Dietary Interventions and Physical Activity as Crucial Factors in the Prevention and Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease. | 2025 | Biomedicines | PMID 39857800 | As with the ketogenic diet, due to the abundance of diverse protocols for this dietary model, it is difficult to generalize the results of the studies to date; despite this, an umbrella review of 11 meta-analyses and 13… |
O que a evidência parece apoiar
Os artigos acima foram retornados por uma busca do LitSource com fontes para esta afirmação. Trate-os como evidência candidata: revise o trecho destacado e abra o artigo original antes de citar.
O que continua incerto
Este rascunho não classifica certeza clínica, não substitui métodos de revisão sistemática e não decide se a afirmação deve ser usada em cuidado médico. Verifique desenho do estudo, população, intervenção, tamanho do efeito e atualidade antes de usar qualquer citação.
Teste esta busca no LitSource
Cole a afirmação no LitSource para executar a busca novamente, revisar trechos de evidência atualizados e exportar citações.