Evidence Brief: Is coffee consumption associated with cardiovascular risk?

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Research question

Is coffee consumption associated with cardiovascular risk?

Short answer

The returned literature should be checked for dose, population, cardiovascular endpoint, and whether the evidence is observational.

Search conditions and results

  • Claim searched: Coffee consumption is associated with cardiovascular risk outcomes.
  • Search intent: Find source-linked biomedical papers about coffee consumption and cardiovascular risk.
  • Result set: Top source-linked biomedical papers returned by LitSource for this claim.
  • Last refreshed: 2026-05-04

Top papers found

PaperYearJournalSourceEvidence snippet
Misclassification of coffee consumption data and the development of a standardised coffee unit measure.2019BMJ nutrition, prevention & healthPMID 33235952We recently highlighted that aside from pregnancy, coffee consumption is more likely to be beneficially, rather than harmfully, associated with health outcomes, including lower risk of all-cause mortality, cardiovascula…
Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes.2017BMJ (Clinical research ed.)PMID 29167102The conclusion of benefit associated with coffee consumption was supported by significant associations with lower risk for the generic outcomes of all cause mortality, cardiovascular mortality, and total cancer.
Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies.2014CirculationPMID 24201300To examine the dose response association of coffee consumption with cardiovascular disease risk, we conducted a systematic review and meta-analysis of coffee consumption and incidence of total CVD outcomes, including in…
Coffee consumption and plasma total homocysteine: The Hordaland Homocysteine Study.1997The American journal of clinical nutritionPMID 8988925We report on an association between coffee consumption and the concentration of total homocysteine (tHcy) in plasma, a risk factor for cardiovascular disease and for adverse pregnancy outcome.
Caffeine and cognitive decline in elderly women at high vascular risk.2013Journal of Alzheimer's disease : JADPMID 23422357Given the growing number of studies suggesting caffeine may have a vascular protective effect and the lack of major adverse outcomes associated with caffeine consumption among groups at high cardiovascular risk, caffein…
Long-term outcomes from the UK Biobank on the impact of coffee on cardiovascular disease, arrhythmias, and mortality: Does the future hold coffee prescriptions?2023Global cardiology science & practicePMID 37351100Light-to-moderate coffee consumption(0.5-3 cups per day) has been shown to be beneficial for a range of cardiovascular conditions, including coronary artery disease(CHD), arrhythmias heart failure and stroke leading to…
Caffeine and Cardiovascular Outcomes: Current Evidence and Clinical Perspectives.2026Cardiology in reviewPMID 41945865Acute exposure can produce increases in blood pressure, alterations in sympathetic activity, and changes in ventricular ectopy, whereas habitual coffee consumption is associated in cohort studies with neutral or modestl…
Coffee for Cardioprotection and Longevity.2018Progress in cardiovascular diseasesPMID 29474816Habitual coffee consumption is also associated with lower risks for cardiovascular (CV) death and a variety of adverse CV outcomes, including coronary heart disease (CHD), congestive heart failure (HF), and stroke; coff…

What the evidence appears to support

The papers above were returned by a source-linked LitSource search for this claim. Treat them as candidate evidence: inspect the highlighted snippet, then open the original paper before citing.

What remains uncertain

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